A novel source of collagen for wound healing

Chronic wounds which fail to heal in an expected timeframe pose significant challenges to healthcare systems globally. Factors such as diabetes, aging populations, and increasing rates of obesity contribute to the prevalence of these persistent wounds. Traditional wound care solutions often fall short, necessitating the development of advanced materials that can better support the complex healing process. The ANURAN range of chronic wound products features native Type I collagen derived from amphibian sources and represents a groundbreaking advancement in the field of chronic wound care.

The first pipeline product in this range, ANURAN SP1, is a medical device in the form of a sponge dressing. This product is designed to come into direct contact with wound beds, providing a scaffold and biochemical pathway to recruit fibroblasts post-debridement. The highly absorbable bullfrog collagen in ANURAN SP1 assists in managing wound exudate, reducing inflammation, and facilitating granulation, ultimately leading to wound closure. This microporous scaffold environment enables native cells to colonize and rebuild tissue, promoting natural healing processes.

The bullfrog collagen used in ANURAN SP1 offers several advantages over traditional collagen sources. Its higher biocompatibility compared to bovine or other mammalian collagens minimizes the risk of adverse reactions. Additionally, bullfrog collagen possesses greater tensile strength and better thermostability than marine collagen sources. These properties ensure that the wound dressing remains effective and durable throughout the healing process, providing consistent support for tissue regeneration.

ANURAN SP1's ability to manage exudate is crucial in preventing maceration while maintaining a hydrated environment conducive to healing. Proper hydration is essential for the wound healing process, promoting granulation tissue formation and epithelialization. By maintaining a balanced moisture environment, ANURAN SP1 supports the various stages of wound healing, from the initial inflammatory response to tissue remodeling and maturation, thus reducing the risk of infection and accelerating the healing process.

The microporous nature of ANURAN SP1 not only ensures efficient exudate management but also facilitates optimal wound hydration. This feature is essential for the wound healing process, as it promotes granulation tissue formation and epithelialization. By maintaining a balanced moisture environment, ANURAN SP1 supports the various stages of wound healing, from the initial inflammatory response to tissue remodeling and maturation. This balanced environment helps to reduce the risk of infection and accelerates the healing process.

Developed through a collaboration between scientists at Nanyang Technological University (NTU) in Singapore and Cuprina, ANURAN SP1 is backed by extensive research and innovation. This patented biomaterial harnesses the unique properties of amphibian-derived Type I collagen, making it a superior choice for advanced wound care. With the introduction of ANURAN SP1, Cuprina is set to revolutionize wound care, providing solutions that facilitate accelerated wound closure rates through natural healing mechanisms.